Irritable Bowel Syndrome Management
Overview
Irritable bowel syndrome (IBS) is a chronic condition of the digestive system. Its primary symptoms are abdominal pain and changes in bowel habits (constipation and/or diarrhea).
IBS is very common. An estimated 10 to 20 percent of people experience symptoms of IBS, although only about 15 percent of affected people actually seek medical help.
The chronic nature of IBS and the challenge of controlling its symptoms can be frustrating for both patients and health care providers. However, there are treatments and therapies that can help.
Irritable Bowel Syndrome Causes
There are a number of theories about how and why irritable bowel syndrome (IBS) develops.
Despite intensive research, the cause is not clear.
- One theory suggests that IBS is caused by abnormal contractions of the colon and intestines (hence the term “spastic bowel,” which has sometimes been used to describe IBS). Vigorous contractions of the intestines can cause severe cramps, which may explain why some treatment approaches, such as antispasmodic medications and fibre (both of which help to regulate the contractions of the colon), relieve symptoms in some cases. However, abnormal contractions do not explain IBS in all situations, and it is unclear whether the contractions are a symptom or cause of the disorder.
- Some people develop IBS after a severe gastrointestinal infection (eg, Salmonella or Campylobacter, or a virus). However, it is not clear how the infection triggers IBS to develop, and most people with IBS do not have a history of these infections.
- People with IBS who seek medical help are more likely to suffer from anxiety and stress than those who do not seek help. Stress and anxiety are known to affect the intestine; thus, it is likely that anxiety and stress worsen symptoms.
- Food intolerances are common in patients with IBS, raising the possibility that it is caused by food sensitivity or allergy. This theory has been difficult to prove, although it continues to be studied. The best way to detect an association between symptoms of IBS and food sensitivity is to eliminate certain food groups systematically. This should only be done with the guidance of a doctor or nutritionist in order to make sure you get all the nutrients your body needs. In addition, unnecessary dietary restrictions can have a negative impact on your quality of life.
- A number of foods are known to cause symptoms that mimic or aggravate IBS, including dairy products (which contain a sugar called “lactose”), legumes (such as beans), and cruciferous vegetables (such as broccoli, cauliflower, Brussels sprouts, and cabbage). These foods increase intestinal gas, which can cause cramps. Several medications also have effects on the intestines that may contribute to symptoms.
- Many researchers believe that IBS is caused by heightened sensitivity of the intestines. The medical term for this is “visceral hyperalgesia.” This theory proposes that nerves in the bowels are overactive in people with IBS, so that normal amounts of gas or movement are perceived as excessive and painful. Some patients with severe IBS feel better when treated with medications that decrease pain perception in the intestine (such as certain antidepressants).
Irritable Bowel Syndrome Symptoms
Irritable bowel syndrome (IBS) often begins in young adulthood and is more common in females than in males. The most common symptom of IBS is abdominal pain in association with changes in bowel habits (diarrhea and/or constipation).
Abdominal pain — Abdominal pain is typically crampy and varies in intensity. Some people notice that emotional stress and eating worsen the pain and that having a bowel movement relieves the pain. Some people who menstruate notice an association between pain episodes and their period.
Changes in bowel habits — This is the other symptom typical of IBS. Changes in bowel habits can include diarrhea, constipation, or alternating between diarrhea and constipation.
If diarrhea is the more common pattern, the condition is called “diarrhea-predominant” IBS; if constipation is more common, the condition is called “constipation-predominant” IBS.
Diarrhea — A person with irritable bowel syndrome may have frequent loose stools. Bowel movements usually occur during the daytime, and most often in the morning or after meals.
Diarrhea is often preceded by a sense of extreme urgency and followed by a feeling of incomplete emptying. About one-half of people with IBS also notice mucus discharge with diarrhea. Diarrhea occurring during the night is very unusual with IBS.
Constipation — Constipation of IBS can be intermittent and last for days. Stools are often hard and pellet-shaped. You may not feel empty after a bowel movement, even when the rectum is empty. This faulty sensation can lead to straining and sitting on the toilet for prolonged periods of time.
Other symptoms — Other symptoms of IBS include bloating, gas, and belching.
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Irritable Bowel Syndrome Diagnosis
Several different intestinal disorders have symptoms that are similar to irritable bowel syndrome (IBS).
Examples include malabsorption (when the intestines cannot absorb nutrients normally), inflammatory bowel disease (such as ulcerative colitis and Crohn disease), celiac disease (in which the body is unable to break down a protein called “gluten”), and microscopic colitis (a condition that involves inflammation of the colon).
Because there is no single diagnostic test for IBS, many clinicians’ approach involves comparing your symptoms to formal sets of diagnostic criteria. However, these criteria are not accurate in distinguishing IBS from other conditions in everyone. Thus, a medical history, physical examination, and select tests can help to rule out other medical conditions.
Tests — Most clinicians order routine blood tests in people with suspected IBS; these tests usually come back normal, but they can help rule out other medical conditions.
Some clinicians also order more invasive tests, such as sigmoidoscopy or colonoscopy, especially in people over age 40 years. These are tests that allow the clinician to see the inside of your colon using a device that is inserted into the rectum.
Irritable Bowel Syndrome Treatment
There are a number of different treatments and therapies for irritable bowel syndrome (IBS).
Treatments are often given to reduce the pain and other symptoms of IBS, and it may be necessary to try more than one combination of treatments to find the one that is most helpful for you.
Treating IBS symptoms can take time; during this process, it is important to communicate with your doctor about your symptoms, concerns, and any stressors or other problems that develop.
The first step in treating IBS is usually to monitor your symptoms, daily bowel habits, and any other factors that may affect your bowels. This can help to identify things that worsen symptoms in some people with IBS, such as lactose, other food intolerances, or stress. Keep track of what you ate, what you did, and how you felt each day.
It is reasonable to try avoiding or limiting foods that may aggravate IBS, although it’s best to talk to your doctor before you make significant changes to your diet. Eliminating foods without assistance can potentially worsen symptoms or cause new problems if you aren’t getting the nutrients you need.
Many clinicians recommend temporarily eliminating milk products, since lactose intolerance is common and can aggravate IBS or cause symptoms similar to IBS. The greatest concentration of lactose is found in milk and ice cream, although it is present in smaller quantities in yogurt, cottage and other cheeses, and any prepared foods that contain these ingredients
If your doctor suggests eliminating lactose, you should avoid all lactose-containing products for two weeks. If IBS symptoms improve, it is reasonable to continue avoiding lactose. If symptoms do not improve, you may resume eating lactose-containing foods.
Many foods are only partially digested in the small intestines. When they reach the large intestine (colon), further digestion takes place, which may cause gas and cramps. Eliminating certain foods temporarily is reasonable if gas or bloating is bothersome.
The most common gas-producing foods are legumes (such as beans) and cruciferous vegetables (such as cabbage, Brussels sprouts, cauliflower, and broccoli). In addition, some people have trouble with onions, celery, carrots, raisins, bananas, apricots, prunes, sprouts, and wheat.
Increasing dietary soluble fibre (either by adding certain foods to the diet or using fibre supplements) may relieve symptoms of IBS, particularly if you have constipation . By reading the product information panel on the side of the package, you can determine the number of grams of fibre per serving. Fibre may also be helpful in some people with diarrhea-predominant symptoms since it can improve the consistency of stools.
A fibre supplement may also be recommended to increase fibre intake since it is difficult to consume enough fibre through diet alone. Fibre supplements should be started at a low dose and increased slowly over several weeks to reduce the symptoms of excessive intestinal gas, which can occur in some people when they first start taking supplements.
Fibre can make some people with IBS more bloated and uncomfortable. If this happens, it is best to decrease fibre intake and consider other laxative treatments for constipation.
Stress and anxiety can worsen IBS in some people. The best approach for reducing stress and anxiety depends upon your situation and the severity of your symptoms. Have an open discussion with your healthcare provider about the possible role that stress and anxiety could be having on your symptoms, and together decide upon the best course of action.
- Some people benefit from formal counseling, with or without antidepressant or antianxiety medications. Other treatments, such as cognitive behavioural therapy, may also be helpful. Cognitive behavioural therapy helps you to focus on a particular problem in a limited time period. You learn how your thoughts contribute to anxiety or stress and learn how to change these thoughts.
- Participation in a support group can also be valuable.
- Many people find that physical activity is helpful in maintaining a sense of well-being. Regular exercise can also have favorable effects on the bowels.
IBS is a chronic, life-long condition. Although medications cannot cure IBS, they can help relieve symptoms. The choice among these medications depends in part upon whether your primary symptom is diarrhea, constipation, or pain.
In general, medications are recommended for people whose symptoms have not adequately responded to more conservative measures such as changes in diet and fibre supplements. If you do need medication, your health care provider will work with you to figure out the right approach for your situation.
These medications block the nervous system’s stimulation of the gastrointestinal tract, helping to reduce severe cramping and irregular contractions of the colon. These medications may be particularly helpful when taken preventively (before you have symptoms) and thus are most helpful if you know what triggers your symptoms and predict when they are most likely to happen. Common side effects include dry mouth and eyes and blurred vision.
While primarily used to treat depression, many medications called “tricyclic agents” (TCAs) have a pain-relieving effect in people with IBS. The dose of TCAs is typically much lower than that used for treating depression. It is believed that these medications reduce pain perception when used in low doses, although the exact mechanism of their benefit is unknown.
TCAs commonly used for pain management include Amitriptyline, imipramine, and Nortriptyline. It is common to experience fatigue when starting a TCA; this is not always an undesirable side effect, since it can help improve sleep when TCAs are taken in the evening. TCAs are generally started in low doses and increased gradually. Their full effect may not be seen for three to four weeks.
TCAs also slow movement of contents through the gastrointestinal tract and may be most helpful in people with diarrhea-predominant IBS.
Another class of antidepressants, called “selective serotonin reuptake inhibitors” (SSRIs), may be recommended if you have both IBS and depression. Common SSRIs include Fluoxetine, Sertraline, Paroxetine, Citalopram and Escitalopram.
Other antidepressant medications that may be recommended include Mirtazapine, Venlafaxine and Duloxetine.
A number of herbal and natural therapies have been advertised (especially on the internet) for the treatment of IBS. Unfortunately, there is no evidence supporting their benefit. Although small studies may support some of these therapies, the studies are either too small or have major flaws that make definitive conclusions impossible.
Below are some of the herbal remedies you may have heard about for treating IBS:
Unproven – There is increasing interest in the possible beneficial effects of “healthy” bacteria (probiotics such as acidophilus) in a variety of intestinal diseases, including IBS. Whether supplements containing these bacteria are of any benefit is unproven.
Chamomile tea is of unproven benefit in treating IBS. Furthermore, chamomile can aggravate allergies in people who tend to be allergic to grasses.
Evening primrose oil (a supplement containing gamma linolenic acid) and fennel seeds are also of unproven benefit.
Potentially unsafe – Wormwood is of unproven benefit and may be unsafe; wormwood oil can cause damage to the nervous system. Comfrey is also of unproven benefit and can cause serious liver problems. Iberogast is an herbal product containing nine extracts from medicinal plants . Although thought to be effective in some cases of IBS, cases of acute liver failure have been reported.
Irritable Bowel Syndrome Prognosis
It is important to work with your health care provider to monitor your symptoms over time. If symptoms change, further testing may be recommended. Over time, less than 5 percent of people diagnosed with irritable bowel syndrome (IBS) will be diagnosed with another gastrointestinal condition.
Although IBS can cause substantial physical discomfort and emotional distress, most people are able to control their symptoms and live a normal life without developing serious health problems.